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The concentrations (1.6, 6.4, or 25.6 mM) of L-carnitine were selected based on the physiological concentration in human skeletal muscle (approximately 4.5 mM) (Figure 4)

10.1016/j.biopsych.2012.01.014 [DOI] [PMC free article] [PubMed] [Google Scholar] 24.Wink LK, Adams R, Wang Z, Klaunig JE, Plawecki MH, Posey DJ, et al

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TongJLanXZhangZLiuYSunDWangXet alFerroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis

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Furthermore, adding sodium bicarbonate to buffer local anesthetic solutions like lidocaine and bupivacaine can reduce injection pain by increasing pH, enhancing anesthetic effectiveness