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"GLP-1 receptor agonists and gallbladder disease risk: insights into molecular mechanisms and clinical implications"

Compared to placebo, patients treated with liraglutide lost weight but did not experience less knee pain

RESULTS In ZSF1 obese rats, low-dose semaglutide in the absence of weight loss, significantly improved cardiac function, exercise tolerance, and attenuated fibrosis in the heart and liver

The treated groups showed improvement in hepatic tissue, with nearly regular hepatic cords and sinusoids

Additionally, the high expression of GPX3 may be related to the immunosuppressive state of the TME, with its expression positively associated with plasma cells and M0 macrophages and negatively associated with monocytes and M1 and M2 macrophages (Fig

& Guo, D