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Hoeijmakers, Judith Campisi, Peter L.J
Van Bladeren PJ (ed)
The TRIUMPH-4 Phase 3 data provides the most current safety information: Nausea: 38.1% (9 mg) to 43.2% (12 mg) versus 10.7% placebo Diarrhea: 34.7% (9 mg) to 33.1% (12 mg) versus 13.4% placebo Constipation: 21.8% (9 mg) to 25.0% (12 mg) versus 8.7% placebo Vomiting: 20.4% (9 mg) to 20.9% (12 mg) versus 0% placebo Decreased appetite: 19.0% (9 mg) to 18.2% (12 mg) versus 9.4% placebo The pattern is clear
In REDEFINE 1, which enrolled 3,400 adults without diabetes but with at least one weight-related condition, CagriSema led to an average weight loss of 20.4% at Week 68 , compared to 14.9% with semaglutide, 11.5% with cagrilintide, and 3% with placebo
