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To effectively intervene in oxidative stress damage within hypoxia-related pathological processes, the core strategy targeting the HIF pathway focuses on regulating the generation and homeostasis of pathological ROS, rather than solely addressing hypoxia adaptation itself

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REDEFINE 2 (With Type 2 Diabetes)# 1,206 patients randomized to CagriSema (n=904) or placebo (n=302)