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As summarized in Table 2, preclinical studies in aged animal models revealed a potential relationship between dosing strategy, route of administration, and neurological outcomes

[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Persico AM, Bourgeron T

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The April 2024 paper and a comprehensive 2023 Pharmaceuticals review (PMC10224484) detail how peripheral BPC-157 administration produces corresponding central nervous system effects through multiple mechanisms