Answer: Reported tolerability of these peptides is generally favorable in the literature, but they are not FDA-approved drugs, long-term human safety data is limited, and use should always be medically supervised
Metabolic support helps your training and nutrition still translate into results
Many patients experience persistent weight gain and insulin resistance even with adequate thyroid hormone replacement, suggesting broader metabolic disruption
When it matters more: For patients with normal resting heart rate and no pre-existing cardiac conditions, the increase is generally well-tolerated and not a reason to avoid treatment
Seeff LB, Cuccherini BA, Zimmerman HJ, Adler E, Benjamin SB
Clinical Scenarios Where Ipamorelin Is Sometimes Proposed for Adolescents Despite the absence of evidence, ipamorelin appears in online communities targeting three adolescent scenarios: athletic performance enhancement, body-composition change, and "optimization" in teens with constitutional delay of growth and puberty (CDGP)
