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[2] This is not an incidental formulation choice

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2009 Although Archaea are thought not to have glutamate cysteine ligase (GshA) or glutathione synthase (GshB), key enzymes in glutathione synthesis, there is a report of a putative gamma-glutamylcysteine ligase (GshA) from the archaea Methanosphaera stadtmanae (che in realta' sembra piu' moderno dell'omologo umano) GGT5_HUMAN Functioni Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione-S-conjugate such as leukotriene C4 (PubMed:21447318)

Front Immunol 2018

Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Rokotov, D