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Against those benchmarks, oral agents currently sit at a level of efficacy that is meaningful but measurably lower

Long-term detraining reverses the improvement of lifelong exercise on skeletal muscle ferroptosis and inflammation in aging rats: fiber-type dependence of the Keap1/Nrf2 pathway

While those trials were largely successful, more research is needed to confirm the potential benefits of supplemental TB4 or TB-500

In their study, Chen et al

From the Australian public healthcare perspective, this came at an incremental cost of AU$4.2 billion for SGLT2is and AU$20.2 billion for GLP-1 RAs, with corresponding ICERs of AU$23,717 and AU$100,705 per QALY gained, respectively

Special thanks to all attendees for their engagement and insightful discussions