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In a proof-of-principle experiment, we determined the protein interactome of JQ1

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As a consequence of heightened oxidative stress induced by Aos, the transient receptor potential melastatin 2, a Ca 2+ -permeable channel expressed on brain cells, opens [89]

The researchers found that plasma CoQ10 concentrations were significantly and consistently lower in the ME/CFS patient group

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J Bacteriol 188(2):609618 Kruman II, Culmsee C, Chan SL, Kruman Y, Guo Z, Penix L, Mattson MP (2000) Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity