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It is found in high concentrations in the liver, where it acts as a primary protector against oxidative stress

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This distinction is crucial: most fundamental studies on the actin mechanism focus on the entire T4, and extrapolation to the TB-500 fragment alone remains incomplete in the published literature

Incubating cells with conditioned medium for 24 h resulted in significantly decreased cell viability, which was partially rescued by fer-1 or iron chelation by deferoxamine (Fig