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Gut microbiome shifts require weeks of consistent intervention

While we did not observe any significant changes, there was a general tendency for all three serine doublet mutants to display reduced internalisation in response to GLP-1 stimulation compared to the WT GLP-1R (Fig

1J ), indicating that these three residues are essential for GLP-1(7-36)

Shows up in the first 30 to 60 minutes post-injection, most often during weeks one and two

It's crucial to seek medical attention immediately if you experience severe abdominal pain, persistent vomiting, or signs of an allergic reaction like swelling or difficulty breathing