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Other frequently reported side effects associated with semaglutide may include headache, abdominal pain, nasopharyngitis, dizziness, gastroenteritis, constipation, and GERD.[2] Semaglutide has a boxed warning, or a serious safety warning by the FDA, for the risk of thyroid C-cell tumors.[2] Additional safety warnings and precautions are acute pancreatitis, gall bladder disease, kidney injury, increased heart rate, and hypersensitivity reactions