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Providers can use biomarker context and clinical history to anticipate and mitigate this potential adverse effect

Elevated fluticasone levels increase the risk of systemic corticosteroid side effects, including adrenal suppression, Cushings syndrome, and weakened immune response

Serious side effects are uncommon but can include pancreatitis or dehydration if dosing guidelines aren't followed

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Low to moderate intensity cardio (walking, cycling, light jogging at conversational pace) performed during the 30-60 minute fasting window maximizes fat oxidation from mobilized fatty acids

Cell Metab 33(4):833-844.e5