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Metformin enhances autophagy and normalizes mitochondrial function to alleviate aging-associated inflammation

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Haematologica 2002

However, both liver weights increased

Arai M, Imai H, Koumura T, Yoshida M, Emoto K, Umeda M et al

Protocol at a Glance: Dose: 200-300mcg per injection Frequency: Once daily Best timing: Before bed (aligns with natural GH pulse) or post-workout Method: SubQ injection in abdomen Duration: 3-6 months minimum Cost: $70-100 per month Results Timeline: Week 4-6: Better sleep quality, faster workout recovery Week 8-12: Visible muscle gain, fat loss begins Week 12+: Continued improvement (cumulative effect) Growth hormone peptides require patience