Pinealon restores sleep architecture through pineal gland regulation
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Franois-Xavier Maquart Franois-Xavier Maquart is a researcher/professor at the Laboratory of Biochemistry, Faculty of Medicine, University of Reims, France, collaborating with Jacques-Paul Borel
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Hence, it is likely that NAPQI leads to oxidation of one or more enzymes involved in the conversion of methionine to cysteine, preventing GSH resynthesis from this precursor in phase 2, whereas with NAC such inhibition does not prevent GSH resynthesis.26 Recent studies have provided evidence that cystathionine beta -synthase and cystathionine gamma -lyase, necessary for the conversion of methionine to cysteine, are targets for thiol oxidation by NAPQI.27 Following treatment with NAC, the resulting GSH can act both to detoxify NAPQI by conjugation and to reverse toxicity by thiol reduction
Sep 17 2021;13(9)doi:10.3390/nu13093229 Gana W, De Luca A, Debacq C, et al
