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In a large, multicentre, RCT with selenium, patients with mild Graves orbitopathy significantly improved on treatment with 100 g selenium twice/d (as sodium selenite) for 6 months ( Reference Marcocci, Kahaly and Krassas 7 )

When we combined these LN-related DEGs with 259 ferroptosis-related signatures, we eventually identified 10 differentially expressed ferroptosis regulators (Fig

In rare cases, too much glutathione can cause diarrhea, nausea, vomiting, headaches, or skin rashes

Indeed, enteroids were grown in the same medium whatever the patients metabolic defect, whereas in vivo, the epithelial cell environment is different and probably specific to the metabolic defect

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SURMOUNT-1 Jastreboff AM et al