Kohan (09:55) So Liza, yeah, I was just gonna ask Liza, yeah, you add a point and then Ill ask Liza why
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The most common cause of melanosis coli is the extended use of laxatives, and commonly anthraquinone containing laxatives such as Senna and other plant glycosides
This effect is dose-dependent, and represents a higher risk compared to use of SSRIs (Hirsch & Birnbaum, 2015)(see table)
Magouliotis DE, Tasiopoulou VS, Svokos AA, Svokos KA, Chatedaki C, Sioka E, Zacharoulis D
Studies confirm significant improvements in menstrual cycle regularization, leading to more predictable ovulation patterns Combination therapy shows superior results in androgen reduction , helping restore hormonal balance Clinical trials reveal synergistic effects on metabolic profiles and fertility outcomes Patients experience better ovulation rates and pregnancy success compared to single-drug treatments The dual approach effectively tackles both insulin resistance and hormonal imbalances simultaneously These documented benefits make the combination therapy a promising option for PCOS patients seeking to optimize their fertility potential