Phase 2 results suggested lower nausea and gastrointestinal side effects than has been reported in injectable GLP-1 trials, with more reports of fatigue
Zhang L, Zhang L, Li Y, Li L, Melchiorsen JU, Rosenkilde M, et al
In addition, recent clinical evidence from the AngioSafe T2DM Study demonstrated no association between GLP-1 RAs and severe diabetic retinopathy [107], suggesting that GLP-1 RA does not have a causal influence on retinopathy independent of glucose lowering
Zhu A, Andino J, Daignault-Newton S, Chopra Z, Sarma A, Dupree JM
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Clinical Guidance and Best Practices Because microdosing GLP-1 medications is not an FDA-approved or clinically standardized term or protocol, there are no clinical guidelines or best practices