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RSL3 induces DNA damage, inhibits DNA repair, and promotes autophagy in PTC cells We showed that the RSL3-mediated GPX4 inhibition induced multi-fold rise in intracellular ROS in PTC cells in vitro

Ralli M, Angeletti D, Fiore M, D'Aguanno V, Lambiase A, Artico M, de Vincentiis M, Greco A

Based on these findings, it has been proposed that GSH slows down the disease progression

[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Min T, Bain SC

387,389 Although the exact mechanisms driving these effects remain to be fully clarified, several studies have highlighted the importance of hypoglycemia in triggering the process of liver regeneration following acute liver injury

Neurodegenerative diseases GST polymorphisms have also been associated with neurodegenerative conditions including Alzhaimer and Parkinson diseases (Table 1) 46,47