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Metformin, through the induction of 5' AMP-activated protein kinase and subsequently insulin sensitivity, has been widely used as a therapeutic agent in various conditions, including type 2 diabetes mellitus, PCOS and gestational diabetes (Reference Rice, Elia and Jawad42)
Tu Z, Moss-Pierce T, Ford P, Jiang TA
Hua X, Deng R, Li J, Chi W, Su Z, Lin J, Pflugfelder SC, Li DQ
10.1016/S2213-2600(13)70286-8 Lancet Respir Med
Using heteronuclear nuclear Overhauser effect (hetNOE) experiments, we determined the essential regions of the p53 TAD for binding to the FOXO4 forkhead domain (FHD)
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