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Indeed, others have previously reported that N-OH amphetamine produces amphetamine-like behavioral effects and that, in some assays, it is at least as potent as amphetamine [2,18]

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These results highlight hepsin's crucial role in controlling APAP-induced liver toxicity by regulating the cellular abundance of GJ proteins, which can affect the transmission of toxic metabolites or cell death signals and potentially increase oxidative stress

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doi: 10.1007/s13361-011-0227-4

Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2