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Alternatively, perhaps sites of ER-mitochondrial contact facilitate spatially restricted exchange of glutathione as they do for other metabolites such as calcium and reactive oxygen species (Joseph, Booth, Young, & Hajnoczky, 2019)

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The role of GIP in response to DPP-4 inhibition To test the specific contribution made by GIP to linagliptin-induced improvements in glucose tolerance, a GIP antagonising antibody (GIPrAB) [10] was administered to littermate wild-type and Gcg RA Null mice