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Hypoactive sexual desire disorder (HSDD) and erectile dysfunction unresponsive to PDE5 inhibitors

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Semaglutide is marketed under different brand names (Rybelsus, Ozempic, Wegovy) to reflect different formulations (oral or injectable) and licensed indications (type 2 diabetes or weight management)

DOI: 10.1016/j.amjhyper.2005.03.012 Hartman C (2024): The tyramine intolerance handbook: Prevent migraines, palpitations, anxiety, blood pressure spikes, and more

On glycemic control, it selectively boosts insulin synthesis and secretion from pancreatic -cells when blood glucose rises, meanwhile restraining excessive glucagon release from -cells to cut hepatic glucose overproduction, and protects islet cells against inflammatory apoptosis to preserve long-term pancreatic function

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