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Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as a promising therapeutic option for promoting WL beyond lifestyle modifications, demonstrating efficacy in non-surgical populations [9, 10]

Because the protein fractions are sensitive to heat and aggressive blending, gentle mixing is recommended

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The water-methanol phase containing polar metabolites was dried down and reconstituted with water/acetonitrile (1:1), with the volume normalized to cell number

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