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The in vitro redox-midpoint of GCL (Hicks et al., 2001)

If it goes the estrogen route, androstenedione is converted (using CYP19A1) first to estrone (E1), which is then converted (using 17-HSD) into estradiol.[ref] Here is a flow chart to give you a better idea of the conversion of cholesterol into estrogen, including the genes that are involved

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Recent advancements in the pharmacological treatment of MASLD and MASH have shown promising results, particularly with medications such as Resmetirom and Fibroblast Growth Factor 21 (FGF21) analogs