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10.1016/j.ejpb.2023.09.003

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14.3 POMC, PCSK1, and LEPR Deficiency (Adults and Pediatric Patients Aged 6 Years and Older) Overview of Clinical Trials The efficacy of IMCIVREE for weight reduction in adults and pediatric patients 6 years of age and older with obesity due to POMC, PCSK1, or LEPR deficiency were assessed in 2 identically designed, 1-year, open-label trials, each with an 8week, double-blind withdrawal period

Divide the target dose by the concentration: 0.25 mg 2.5 mg/mL = 0.10 mL Step 3 convert to insulin-syringe units

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