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Half of each resected tumor was flash frozen and stored at 80 C for downstream biochemical analysis, and the remaining half was fixed in a 4% paraformaldehyde solution for histology

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Adipose tissue inflammation Promotes lipolysis (preclinical only) Discover More These indirect effects contribute to decreased fat mass and improved metabolic health

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Additional studies have shown that the upregulation of sirtuin3 (SIRT3) promotes the AMPK-mTOR pathway and reduces GPX4 level to enhance autophagy activation, leading to ferroptosis in trophoblast cells (Han et al., 2020)

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