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Other anamolies of the PDC include autoantibodies leading to paediatric biliary cirrhosis [47].Additionally, the aberrant down-regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation has been shown to be contributory to hyperglycemic states observed in type-2 diabetes [25], increasing the chances of pyruvate dehydrogenase complex as a therapeutic target for a 150 million people affliction i.e

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According to the commentary, the improved motor capacity in those patients could be the result of the enhanced absorption of levodopa rather than the administration of riboflavin (99)

Always consult your metabolic specialist before making any changes to your L-carnitine dosing schedule or sick day protocols

Lo YH, Yang SF, Cheng CC, Hsu KC, Chen YS, Chen YY, et al