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Individuals seeking to reduce general body weight, particularly with an elevated BMI may fare better with drug therapy

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In case of simultaneous administration of glutathione and the chemotherapeutic agent, the intravenous infusion of TAD should be performed 15-30 minutes before the start of chemotherapy

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Management Strategies and When to Contact Your Provider Evidence-based management includes: slower dose titration (extending ramp-up to 812 weeks instead of standard 4 weeks), maintaining adequate protein and micronutrient intake (especially iron and B vitamins, which support thermogenesis), light resistance exercise (preserves muscle mass and metabolic rate), and behavioral strategies like layered clothing and warm beverages