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doi: 10.1039/D2SC00676F 164 LiHDingPPengBMingY-ZJHInternationalPD

A prospective cohort study involving 266 elderly adults treated with epithalamin (the parent compound from which Epithalon was derived) over 2-3 years with subsequent 4-5 year follow-up demonstrated mortality reduction of 28% overall, with a 2-fold decrease in cardiovascular disease-specific mortality

Functioning as a natural HDAC inhibitor, it critically modulates various protein post-translational modifications (PTMs)

Cell 2022;185:240121

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