GIP and GLP-1 have well-established roles in regulating glucose and energy metabolism, whereas GLP-2 is better known for intestinotrophic actions
GLP-1 (glucagon-like peptide-1) receptor agonists are a class of medications that were initially developed to manage type 2 diabetes
GLP-1s can also trigger nausea, cramping or diarrhoea in some people meaning not everyone with IBS-D will benefit
doi: 10.1124/jpet.118.254821 63 TonneijckL.MuskietM
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Below are evidence-based protocols for each compound, as well as a transition protocol for researchers moving between them
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