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Male rats receiving 1.2 mg/kg sertraline cumulatively until postnatal day 126 exhibited significantly reduced male potency (based on various indices of mating and fertility), while cumulative treatment significantly increased the number of fetal congenital malformations and reduced the numbers of implantation sites and surviving fetuses

In patients with moderate (initial) dementia caused by AD and vascular dementia (VD), administration with ALC at dosages of 2.253.0 g/day resulted in a substantial treatment response in individuals with AD relative to placebo-treated and VD patients (Gavrilova et al., 2011)

As a glucagon-like peptide-1 ( GLP-1 ) receptor agonist, tirzepatide, in and of itself, can also influence hormones

Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial

10.1056/NEJMoa1603827 79

doi: 10.1016/s2213-8587(22)00340-0 127 RentzeperiEPegiouSKoufakisTGrammatikiMKotsaK