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As the research community anticipates subsequent phases of the RESTORE trial, the implications extend beyond the clinical sphere into public health domains, where obesity and infertility represent growing burdens with multifactorial etiologies

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Exposing the brain of either vehicle- or DMF-treated animals to CDNB in these conditions did not induce any detectable alteration in the staining of either claudin-1 or claudin-2, two major proteins associated in the brain with choroidal epithelium tight junctions, as assessed by epifluorescence and confocal microscopy (Additional file 2)

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