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In the RSSH structure, the sulfane sulfur atom is the outer sulfur with -1 oxidation state, while in elemental sulfur (S 8 ) or in polysulfides (RSSSR) the oxidation state of sulfane sulfur atom is 0

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Extrapolating mecasermin data to IGF-1 LR3 is problematic because the pharmacokinetics and tissue exposure profiles differ significantly due to the binding protein modifications

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In vitro GSH sensitivity and selectivity experiments The HT adducts were prepared by combining the HT protein (~50 M in PBS) with the respective TRaQ-G ligand (1.52 excess, stock solution 50 mM in DMSO) and rotating the resulting solution for 1 h at 20 C