Diabetologia 14 , 413417 (1978)
Of note, this trial employed an individualized titration schedule on a variety of background regimens, which is likely more applicable to typical clinical practice
What to Expect in Your Labs Triglyceride reductions on GLP-1 medications tend to appear relatively early compared to other metabolic improvements, often within the first two to three months of treatment as weight loss begins and dietary patterns shift
The 'Switch' is On: Proving the Viability of Oral Maintenance Therapy The ATTAIN-MAINTAIN study was a first-of-its-kind Phase 3 trial designed to answer a critical clinical question: can patients who have successfully lost weight on injectable GLP-1s (Wegovy or Zepbound) switch directly to an oral agent and maintain their results
For example, if a patient is taking three medications for high blood pressure and successfully loses weight on Wegovy, she said there is a good chance that one, two, or even all three of the patients antihypertensives could be discontinued
Theres no tapering-off regimen either, but thats true about many other medications, he notes
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