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[DOI] [PubMed] [Google Scholar] 246.Gadde KM, Allison DB, Ryan DH, et al

I am NOT advising you to follow my possibly questionable practice, but, when I knew we were going through Brexit I took note of the expiry dates of ampoules that were being issued at the time and chose to buy enough ampoules to last me for a year beyond their expiry date - working on the principle it might take a couple of years for the supply chain to work itself out and I didn't want to run out

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Since for most people it is impractical to take supplements several times a day, a single dosage of 250-500 micrograms seems to be the best solution