glutathione and zinc interaction Cellular metabolism zinc signaling: from biological functions to diseases and therapeutic targets Antioxidant Metabolism Pathways in Vitamins,

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Although the antioxidant capacity of flavonoids may be compromised after reacting with ROS, recent studies have shown that the oxidized derivatives of certain flavonoids can significantly enhance their original antioxidant properties by activating the NRF2/KEAP1 pathway and upregulating the cell's endogenous antioxidant capacity [423]