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A conjugation of AITC to glutathione in planta might be non-enzymatic or catalysed by GSTs, as indicated by the AITC-induced upregulation of several GST-encoding genes 17,40,41 and similar to what was recently shown for indol-3-ylmethyl-ITC 35

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Tirzepatide weight-loss dose-tier guide What each dose did in SURMOUNT-1 (obesity, no diabetes, 72 weeks) Weekly dose 5 mg Average weight loss 16.0% Plain-English read First real treatment dose

they work by mimicking natural hormones to regulate appetite and promote gradual, sustainable weight loss