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What the Data Shows The honest answer, based on the published evidence, is mixed rather than negative

GLP-1 tapering and long-term weight management If youre taking a GLP-1 for type 2 diabetes, you will likely stay on your maintenance dose unless your doctor recommends otherwise

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Diet and exercise still matter

When youre taking semaglutide or another GLP-1, they can help you monitor your progress and recommend medication adjustments as needed for as long as theyre helping you achieve your goals

At the 12 mg dose, mean HbA1c reductions from baseline reached approximately 2.2 percentage points (around 24 mmol/mol) at 24 weeks