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announced that the FDA has approved WEGOVY as the first GLP-1 receptor agonist for adults with Metabolic Dysfunction-associated Steatohepatitis (MASH) who have moderate to advanced fibrosis, excluding In August 2025, Novo Nordisk cirrhosis , in combination with diet and exercise

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Like alcohol use, chronic GHB use can lead to tolerance, dependence, addiction, and withdrawal symptoms

Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon