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Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
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A 2020 review of peptide drug stability published in the European Journal of Pharmaceutics and Biopharmaceutics noted that lyophilized formulations retain greater than 95% potency when kept at or below 8 C and protected from light and moisture [4]
However, another study reported that a group of T2DM patients treated with metformin plus liraglutide or metformin plus Ex-4 for 1 year experience an increase in resting energy expenditure compared to placebo treated controls when energy expenditure was adjusted for fat free mass (Beiroa et al., 2014)