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Summary-level GWAS statistics for AD were obtained from the publicly available meta-analysis by Bellenguez et al

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A practical strategy includes: Starting the day with a high-fibre breakfast, such as porridge with berries and ground flaxseed Including vegetables with both lunch and dinner Choosing wholegrain varieties of bread, pasta, and rice Ensuring adequate fluid intake (6-8 glasses daily) Considering a psyllium supplement if dietary measures prove insufficient (taken with plenty of water and separated from other oral medicines by at least 2 hours) Patients should contact their GP if constipation persists despite these measures, as additional interventions may be required

A compound that helps grow new vasculature into poorly perfused tissue is, at least in theory, aimed squarely at the root of the issue

Any energy improvements reported by patients typically result from progressive weight loss and metabolic improvements rather than direct pharmacological effects on energy production

Evercore analyst Umer Raffat said he thinks Pfizer is likely buying some time to see how a different obesity pill its studying performs