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For lupus patients specifically, tirzepatide's dual-receptor activation may offer advantages over single-action semaglutide in managing corticosteroid-induced weight gain and visceral fat accumulation

SIM is characterized by its systemic and symmetrical nature, presenting with weakness in the limbs (more proximal than distal) and respiratory muscles, while facial and ocular muscles are generally unaffected (13-15)

Avoid using Clarithromycin with statins unless specifically advised

Usually weekly for the first month, then every 24 weeks depending on your response and baseline levels

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