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The substrates generated in this pathway are essential for synthesizing numerous molecules, including nucleic acids, steroids, and neurotransmitters (34, 37)

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We are really only concerned about toxicity from fat-soluble vitamins (A, D, E, and K)

Optimization of the Caco-2 permeability assay to screen drug compounds for intestinal absorption and efflux

Saffron increased several short-chain-fatty-acidproducing genera and the researchers noted some correlations between microbiota changes and sleep parameters, but the study was too preliminary to allow clear conclusions about the extent to which saffrons effects on sleep are mediated by changes in the gut microbiota

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