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It is considered the master regulator of inflammation, controlling the expression of hundreds of genes involved in immune activation, cytokine production, and cell survival

Similar content being viewed by others Introduction The integrity of our genome is constantly challenged by DNA damaging agents present in the environment or that arise during cellular metabolism

Not in an observational study

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Laboratory research demonstrates that FOXO4-DRI's selectivity stems from exploiting fundamental differences between senescent and healthy cell biology, particularly the paradoxical state where senescent cells are primed for apoptosis but protected by specific survival mechanisms