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Three minutes minimum

[DOI] [PubMed] [Google Scholar] 12.Gleason P.P., Urick B.Y., Marshall L.Z., Friedlander N., Qiu Y., Leslie R.S

Patients should remain upright for at least 2-3 hours after meals, particularly dinner, to facilitate digestion and reduce discomfort

doi: 10.1002/oby.23930

But it is also important for even common and everyday drugs, like ibuprofen, which can become caustic to the stomach or intestines if they are taken without food or allowed to sit in the stomach when not diluted

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