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93 These side effects are caused mainly by the low selectivity of the drugsinhibiting CPTI in target spot as well as in normal ones, leading to metabolic disorder

( C ) Representative histogram showing flow cytometry analysis of sorted CD105 + EPCR + endothelial cells (left) and heatmap showing differentially regulated genes in endothelial cells (right) from PAR2-G37I, PAR2-R38E, and WT mice ( n = 3/4/4)

(1) Improve weight loss and loss of appetite Cancer cachexia is one of the common complications in cancer patients, characterized by weight loss, loss of appetite, muscle atrophy, and fatigue

First, it stimulates fibroblast proliferation, which increases collagen and elastin production

Nature 594 , 448453 (2021)