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e , Relative abundance of SLC25A39, GCLM and SLC25A40 transcripts in HEK-293T cells treated with BSO (1 mM) for the indicated days using quantitative reverse transcription PCR (RT-qPCR), normalized to transcripts of -ACTIN

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Collagen metabolism and molecular mechanisms of EDS The concept that EDS is a disorder of fibrillar collagen metabolism is well supported by identification of specific defects in the collagen biosynthetic pathway that produce clinically distinct forms of EDS

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