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It plays a critical role in regulating metabolic functions, improving insulin sensitivity, and promoting cellular energy production

By strengthening intestinal integrity and reducing inflammatory cytokine production, semaglutide and tirzepatide may address underlying drivers of widespread pain and fatigue rather than masking symptoms alone

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Z Gastroenterol 34:159166 Hansen L, Lampert S, Mineo H, Holst JJ (2004) Neural regulation of glucagon-like peptide-1 secretion in pigs