The bottom line The potential for side effects from weight-loss medication isnt something to minimize or just try to power through
These effects are seen even outside of diabetes control.[ref] Decreased colon cancer mortality: A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)
Constipation on GLP-1 Therapy: Why It Should Not Be Ignored Constipation is more than an inconvenience
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Although Ozempic was initially approved specifically for diabetes management, it has gained attention due to its demonstrated ability to support significant weight loss in clinical studies
The medications work as a GIP and GLP-1 receptor agonists, activating the hormone receptors and working to slow digestion and, in turn, increase satiety and reduce food cravings
